Eicosanoids, SPM & Vascular Pharmacology

Human vascular tissue research
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Host laboratory for BA, Master and PhD Thesis, contact: xnorel@hotmail.com,  INSERM U1148, Laboratory for Vascular Translational Science (LVTS). CHU X. Bichat, 46, rue Henri Huchard, 75877 Paris Cedex 18, France. Access, map. Tel: 33 1 40 25 75 29
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Last update: 13/05/25

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Reference table Prostanoid receptors in human pulmonary vessels

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  • Benyahia C., Boukais K, Gomez I, Silverstein A, Clapp L, Fabre A, Danel C, Leséche G, Longrois D, Norel X. A comparative study of PGI2 mimetics used clinically on the vasorelaxation of human pulmonary arteries and veins, role of the DP-receptor. Prostaglandins Other Lipid Mediat. 2013 Dec;107:48-55.
  • Haye-Legrand, I., Bourdillat, B., Labat, C., Cerrina, J. Norel, X., Benveniste, J. and Brink, C. Relaxation of isolated human pulmonary muscle preparations with prostacyclin (PGI 2) and its analogs. Prostaglandins, 33 : p 845-854, 1987.
  • Maddox, Y., Cunard, C.M., Shapiro, R., Kawaguchi, A., Goldman, M., Lower, R.R. and Ramwell, P.W . A comparison of the contractile responses of rodent and human pulmonary vascular segments to eicosanoids. In Prostaglandins, Leukotrienes and Lipoxins. Elsevier, Martin Bailey-J. pp. 267-272, 1985.
  • McKenniff, M., Rodger, I.W., Norman, P. and Gardiner, P.J. Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways. Eur. J. Pharmacol. 153, p 149-159, 1988.
  • Norel, X., Labat, C., Gardiner, P. and Brink, C. Prostanoid contractions in human isolated pulmonary muscle preparations : inhibition by BAY u3405. Adv. Prostaglandin, Thromboxane and Leukotriene Research., 21: 473-476, 1990.
  • Norel, X., Labat, C., Gardiner, P. and Brink, C. Inhibitory effects of BAY u3405 on prostanoid-induced contractions of human isolated pulmonary muscle preparations. Br. J. Pharmacol. 104 : p 591-595, 1991.
  • Norel X., Walch L., Labat C., Gascard J.P., Dulmet E. & Brink C. Prostanoid receptors involved in the relaxation of human bronchial preparations. Br. J. Pharmacol., 126 (4), 867-872, 1999.
  • Quian, Y.M., Jones, R.L., Chan, K.M., Stock, A.I. and Ho, J.K.S. Potent contractile actions of prostanoid EP3-receptor agonists on human isolated pulmonary artery. Br. J. Pharmacol. 113, p 369-374, 1994.
  • Reinheimer, T., Harnack, E., Racke, K., Wessler, I. Prostanoid receptors of the EP3 subtype mediate inhibition of evoked [3H]acetylcholine release from isolated human bronchi. Br. J. Pharmacol., 125 (2), 271-276, 1998.
  • Walch L., Labat C., Gascard J.P., de Montpreville V., Brink C. & Norel X. Prostanoid receptors involved in the relaxation of human pulmonary vessels. Br. J. Pharmacol., 126 (4), 859-866, 1999.
  • Walch L, de Montpreville V, Brink C, Norel X. Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins. Br J Pharmacol., 134(8), 1671-8, 2001.
  • Foudi N, Kotelevets L, Louedec L, Leséche G, Henin D, Chastre E, Norel X. Vasorelaxation induced by prostaglandin E(2) in human pulmonary vein: role of the EP(4) receptor subtype. Br J Pharmacol. 2008.